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Turkish Journal of Cancer
1993, Volume 23, Number 3, Page(s) 118-125
[ Summary ]
Primary non-Hodgkin’s lymphoma of the stomach: Diagnostic findings and treatment results
İBRAHİM BARIŞTA, GÜLTEN TEKUZMAN, İBRAHİM H. GÜLLÜ, ÖZGÜR ÖZYILKAN, YAVUZ ÖZlŞlK, NİLÜFER GÜLER, AYŞE KARS, EŞMEN BALTALI, EMİN KANSU, DİNÇER FIRAT
Department of Medical Oncology, Hacettepe University Institute of Oncology, Ankara-Turkey

Forty consecutive patients, seen between 1973 and 1990, (with primary gastric non-Hodgkin’s lymphoma) were studied retrospectively in order to evaluate diagnostic findings and treatment results. According to the Working Formulation (WF); 12 patients had low-grade, 20 had intermediate-grade, and 8 had high-grade histologic subtypes. Eighteen cases were diagnosed by endoscopic biopsies, 22 through laparotomy. All patients who did not undergo laparotomy were staged with lymphangiography or abdominal ultrasonography and/or computed tomography. The stage was I or II in 29 cases, Ill in 3, and IV in the remaining 8. Treatment modalities included surgery (S), chemotherapy (CT), radiotherapy (RT). Out of 33 patients who were evaluable for response, 16 had achieved complete remission. The modalities combined in those attaining remission were as follows: S + CT in 5 cases, S + RT in 2 cases, S + CT + RT in 3 cases, CT only in 6 cases. No substantial differences in response to therapy and survival were found in relation to the different treatments. Patients in stage I (n=14) and stage II (n=15) had 5 year disease-free survivals of 55.1% and 48.3%, 5 year overall survivals of 64.3% and 57.0%, respectively. These findings, together with data from the literature, suggest that surgery plus chemotherapy and/or radioherapy may be the therapeutic procedure in clinically assessed early-stage patients. The CT and/or RT can be effective in unresected and even bulky cases, providing there is minimal risk of severe hemorrhage or perforation.

[ Summary ]
Turkish Journal of Cancer web sitesi Novartis Onkoloji'nin karşılıksız eğitim katkılarıyla hazırlanmıştır.
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