T-cell rich B-cell lymphomas are a morphologically and probably biologically heterogeneous group of non-Hodgkin’s lymphomas containing scattered large L26 positive B-cells among the majority of reactive small UCHL-1 positive T-cells. This type of lymphoma seems to be a morphologic variant of large B-cell lymphomas rather than a distinct entity. These lymphomas must be distinguished from peripheral T-cell lymphomas and Hodgkin’s lymphoma on the basis of immunologic and when available, genotypic analysis. The rarity of T-ceIl rich B-cell lymphoma and the unusual aggressive course in this case, which conflicts with the general statement claiming an apparently higher survival rate than T-cell lymphomas, make this rare entity worth to be reported.